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2, that the proper procedures for informed consent with the local indigenous community are put in place and procedures for reciprocity and equitable benefit sharing. So it’s very important for us to make sure that any source of supply that’s being imported from overseas, it’s being done sustainably, No. We’ve been working with groups in West Africa, in Gabon, where the iboga plant is indigenous and, in fact, is also involved with important cultural practices by the Bwiti people. How does that work?Ī: The iboga plant, which contains the psychedelic ibogaine, is probably the best example of that at Filament. Q: Your company also prioritizes ethically and sustainably harvesting these plants. After all, these substances did evolve in nature alongside humans.

Q: Do you think patients will be able to tell the difference when they take these drugs?Ī: It’s our hypothesis that the presence of these other compounds may contribute to differences or perhaps even improvements in the therapeutic potential of these complex natural mixtures. There’s a whole entourage of different compounds, which in the case of coffee gives it a flavor, aroma and terroir. Just like when you drink a cup of coffee there is much more than just caffeine. They contain other compounds like psilocin and a dozen or more other active ingredients. Since our products come from natural sources, we believe it allows people to maintain a certain connection to how humans have been ingesting these substances for years and years and to important aspects of many traditional communities.Ī natural product contains much more than just one single active compound, right? And so in the case of magic mushrooms, for instance, they contain much more than just psilocybin. It’s only recently that we had access to synthetic chemical manufacturing techniques. Q: What do you mean by “natural psychedelics” and how are they produced?Ī: It means we’re deriving them from natural sources, like plants and fungi, because that is in fact the way that humanity has been interacting with these substances in their natural form for thousands of years. The answers have been edited for length and clarity. And more than a dozen other companies and academic centers are using the company’s drugs in trials of depression, chronic pain and other disorders.įilament CEO Benjamin Lightburn spoke with The Associated Press about the ethical, therapeutic and medical case for using naturally derived psychedelics. In this crowded field, Vancouver-based Filament Health has a unique approach: extracting drugs like psilocybin and mescaline from natural sources, including mushrooms and cacti, rather than synthesizing the ingredients in a laboratory.įilament is studying its mushroom-based psilocybin as a treatment for opioid and stimulant use disorder.

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Free Press 101: How we practise journalismĪ recent boom in psychedelic research has given way to a bumper crop of startups seeking to harness the potential of mind-altering drugs for treating depression, addiction and other conditions.